Load Balancing of Tasks on Cloud Computing Using Time Complexity of Proposed Algorithm

Cloud Computing is a developing field and lean toward by numerous one at current yet it's rage is part more rely upon its execution which thusly is excessively rely upon the powerful booking algorithm and load adjusting . In this paper we address this issue and propose an algorithm for private cloud which has high throughput and for open cloud which address the issue of condition awareness likewise with execution. To enhance the throughput in private cloud SJF is utilized for planning and to conquer shape the issue of starvation we utilize limited pausing. For stack adjusting we screen the heap and dispatch the activity to the minimum stacked VM. To acquire advantage and to have open door for future upgrade out in the open cloud condition cognizance is the key factor and for better execution and load adjusting likewise wanted. While stack adjusting enhances the execution, the earth awareness increment the benefit of cloud suppliers

Large sized moustached Thryssa, Thryssa mystax (Bloch & Schneider, 1801) recorded from Cochin coast in Kerala

Two large sized specimens of Thryssa mystax (Family: Engraulidae) were caught in Chooda valai and landed at Chellanam fish landing centre on 20th July 2013. The specimens measured 24.8 cm (Fig. 1) and 24 cm in total length and weighed 100 g and 80 g respectively. These sizes of this species are recorded for the first time in the world

Critical review of Aushadha Sevana Kaala

Aushadha Sevana Kaala or the time of administration of medicine is a very unique concept pertaining to our science of Ayurveda. Even then our understanding about it is more textual than practical. Also its practice is also limited only to a few Ayurveda Vaidyas. An attempt is being made in this article to review the possible references of Aushadha Sevana Kaala, and also try and understand the way they enhance therapeutic action of a medicine

MicroRNA-940 suppresses prostate cancer migration and invasion by regulating MIEN1.

BACKGROUND: MicroRNAs (miRNAs) are crucial molecules that regulate gene expression and hence pathways that are key to prostate cancer progression. These non-coding RNAs are highly deregulated in prostate cancer thus facilitating progression of the disease. Among the many genes that have gained importance in this disease, Migration and invasion enhancer 1 (MIEN1), a novel gene located next to HER2/neu in the 17q12 amplicon of the human chromosome, has been shown to enhance prostate cancer cell migration and invasion, two key processes in cancer progression. MIEN1 is differentially expressed between normal and cancer cells and tissues. Understanding the regulation of MIEN1 by microRNA may enable development of better targeting strategies. METHODS: The miRNAs that could target MIEN1 were predicted by in silico algorithms and microarray analysis. The validation for miRNA expression was performed by qPCR and northern blotting in cells and by in situ hybridization in tissues. MIEN1 and levels of other molecules upon miRNA regulation was determined by Western blotting, qPCR, and immunofluorescence. The functional effects of miRNA on cells were determined by wound healing cell migration, Boyden chamber cell invasion, clonal and colony formation assays. For knockdown or overexpression of the miRNA or overexpression of MIEN1 3'UTR, cells were transfected with the oligomiRs and plasmids, respectively. RESULTS: A novel miRNA, hsa-miR-940 (miR-940), identified and validated to be highly expressed in immortalized normal cells compared to cancer cells, is a regulator of MIEN1. Analysis of human prostate tumors and their matched normal tissues confirmed that miR-940 is highly expressed in the normal tissues compared to its low to negligible expression in the tumors. While MIEN1 is a direct target of miR-940, miR-940 alters MIEN1 RNA, in a quantity as well as cell dependent context, along with altering its downstream effectors. The miR-940 inhibited migratory and invasive potential of cells, attenuated their anchorage-independent growth ability, and increased E-cadherin expression, implicating its role in mesenchymal-to-epithelial transition (MET). CONCLUSIONS: These results, for the first time, implicate miR-940, a regulator of MIEN1, as a promising novel diagnostic and prognostic tool for prostate cancer

Intersection of Smoking, Human immunodeficiency virus/acquired immunodeficiency syndrome and Cancer: Proceedings of the 8 th Annual Texas Conference on Health Disparities

The Texas Center for Health Disparities, a National Institute on Minority Health and Health Disparities Center of Excellence, presents an annual conference to discuss prevention, awareness education and ongoing research about health disparities both in Texas and among the national population. The 2013 Texas Conference on Health Disparities brought together experts, in research, patient care and community outreach, on the "Intersection of Smoking, Human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) and Cancer". Smoking, HIV/AIDS and cancer are three individual areas of public health concern, each with its own set of disparities and risk factors based on race, ethnicity, gender, geography and socio-economic status. Disparities among patient populations, in which these issues are found to be comorbid, provide valuable information on goals for patient care. The conference consisted of three sessions addressing "Comorbidities and Treatment", "Public Health Perspectives", and "Best Practices". This article summarizes the basic science, clinical correlates and public health data presented by the speakers

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Not AvailableTwo large sized specimens of Thryssa mystax (Family: Engraulidae) were caught in Chooda valai and landed at Chellanam fish landing centre on 20th July 2013. The specimens measured 24.8 cm (Fig. 1) and 24 cm in total length and weighed 100 g and 80 g respectively. These sizes of this species are recorded for the first time in the world.Not Availabl

Physicians’ Perspectives on AI in Clinical Decision Support Systems: Interview Study of the CURATE.AI Personalized Dose Optimization Platform

BackgroundPhysicians play a key role in integrating new clinical technology into care practices through user feedback and growth propositions to developers of the technology. As physicians are stakeholders involved through the technology iteration process, understanding their roles as users can provide nuanced insights into the workings of these technologies that are being explored. Therefore, understanding physicians’ perceptions can be critical toward clinical validation, implementation, and downstream adoption. Given the increasing prevalence of clinical decision support systems (CDSSs), there remains a need to gain an in-depth understanding of physicians’ perceptions and expectations toward their downstream implementation. This paper explores physicians’ perceptions of integrating CURATE.AI, a novel artificial intelligence (AI)–based and clinical stage personalized dosing CDSSs, into clinical practice. ObjectiveThis study aims to understand physicians’ perspectives of integrating CURATE.AI for clinical work and to gather insights on considerations of the implementation of AI-based CDSS tools. MethodsA total of 12 participants completed semistructured interviews examining their knowledge, experience, attitudes, risks, and future course of the personalized combination therapy dosing platform, CURATE.AI. Interviews were audio recorded, transcribed verbatim, and coded manually. The data were thematically analyzed. ResultsOverall, 3 broad themes and 9 subthemes were identified through thematic analysis. The themes covered considerations that physicians perceived as significant across various stages of new technology development, including trial, clinical implementation, and mass adoption. ConclusionsThe study laid out the various ways physicians interpreted an AI-based personalized dosing CDSS, CURATE.AI, for their clinical practice. The research pointed out that physicians’ expectations during the different stages of technology exploration can be nuanced and layered with expectations of implementation that are relevant for technology developers and researchers

Understanding the user: Patients' perception, needs, and concerns of health apps for chronic constipation

10.1177/20552076221104673DIGITAL HEALTH